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Therefore identification of the novel drug target and potent drug can be helpful in better prevention of the disease. Alter et.al, (2008) Leprosy as a genetic model for susceptibility to common infectious disease, Hum Genet 2. (1999)Health Policy and Planning; 14(2): 89-102, Oxford University Press.

The bacteria have developed resistance against many of the drugs available in the market.

Palmberg, "Hydraulic transformers-comparison of different designs," 2004.

It is an opportunity for us to reflect on the language and ideas that represented each year.The hydraulic resisting forces, piston speed and mass flow rates are computed. Chenoweth, Aircraft flight control actuation system design vol. Results show that the hydraulic resistance is significantly reduced in the proposed four ports actuators; and the proposed cylinders run faster than the conventional cylinders and a considerable amount of energyis saved as well. Halgamuge "Self-Organizing Hierarchical Particle Swarm Optimizer With Time Varying Acceleration Coefficients" IEEE Trans. A well organized research comprising of analogue based drug design and molecular dynamics plays a major role in obtaining the lead molecules. Black PN, Di Russo CC, Metzger AK, Heimert TL (1992): Cloning, sequencing, and expression of the fad D gene of Escherichia coli encoding Acyl coenzyme A Synthetase. Gao Yue-lin , Duan Yu-hong "A New Particle Swarm Optimization Algorithm with Random Inertia Weight and Evolution Strategy" International Conference on Computational Intelligence and Security Workshops 2007. Guimin Chen, Xinbo Huang, Jianyuan Jia and Zhengfeng Min " Natural Exponential Inertia Weight Strategy in Particle Swarm Optimization" 6th World Confress on Intelligent Control and Automation, June 21 - 23, 2006, Dalian, China. Jong-Bae Park, Yun-Won Jeong, Hyun Houng Kim and Joong-Rin Shin "An Improved Particle Swarm Optimization for Economic Dispatch with Valve-Point Effect" International Journal of Innovations in Energy Systems and Power, Vol. Therefore by emphasizing this protein as a drug target can help in the identification of novel drugs to cure leprosy. Black PN, Zhang Q, Weimar JD, Di Russo CC (1997): Mutational analysis of a fatty Acyl-coenzyme A Synthetase signature motif identifies seven amino acid residues that modulate fatty acid substrate specificity. Key words: cellular genetic algorithm, dynamic optimization, density dependence scheme Reference [1] R.

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